Introduction: In this study, we investigated the effect of intravenous ketamine administration on the treatment of acute abdominal pain in lead poisoning patients. Methods: In this cross sectional study, we evaluated 20 patients with opium abuse with acute abdominal pain. With cardiac monitoring, 0.25 mg/kg ketamine (maximum dose was considered as 20 milligrams) was administered during 30 to 60 seconds. To control ketamine complications 0.03 mg/kg midazolam (maximum dose was considered as 2 milligrams) was injected slowly during one or two minutes. Patients were observed in the ED for the next 6 hours. Pain score was assessed based on VAS with a serial method, before ketamine administration, every hour for the next two hours and every two hours for four hours. Results: In this study 20 patients were enrolled with mean age of 37.2 ± 4.2 years (range from 30 to 44 yrs.). Repeated measurement test shows significant reduce in pain score after ketamine administration (P=0.001). Five patients report no pain 4 hours after ketamine injection, and 3 of them left the hospital with personal consent. From 17 remaining patients, 13 ones (76.4%) had no pain, and mean VAS score in other 4 patients was 1 or 2. Conclusion: our results show that single dose injectable ketamine is one of the best methods with the least side effects to alleviate acute abdominal pain in patients with drug abuse.
| Published in | Clinical Medicine Research (Volume 12, Issue 1) |
| DOI | 10.11648/j.cmr.20231201.12 |
| Page(s) | 9-12 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2023. Published by Science Publishing Group |
Acute Abdominal Pain, Lead Poisoning Patients, Ketamine
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APA Style
Shaghayegh Rahmani, Rana Kolahi Ahari, Hamed Shokoohsaremi, Roohie Farzaneh, Mohammad Davood Sharifi. (2023). Ketamine in Acute Abdominal Pain in Patients with Lead Poisoning. Clinical Medicine Research, 12(1), 9-12. https://doi.org/10.11648/j.cmr.20231201.12
ACS Style
Shaghayegh Rahmani; Rana Kolahi Ahari; Hamed Shokoohsaremi; Roohie Farzaneh; Mohammad Davood Sharifi. Ketamine in Acute Abdominal Pain in Patients with Lead Poisoning. Clin. Med. Res. 2023, 12(1), 9-12. doi: 10.11648/j.cmr.20231201.12
AMA Style
Shaghayegh Rahmani, Rana Kolahi Ahari, Hamed Shokoohsaremi, Roohie Farzaneh, Mohammad Davood Sharifi. Ketamine in Acute Abdominal Pain in Patients with Lead Poisoning. Clin Med Res. 2023;12(1):9-12. doi: 10.11648/j.cmr.20231201.12
@article{10.11648/j.cmr.20231201.12,
author = {Shaghayegh Rahmani and Rana Kolahi Ahari and Hamed Shokoohsaremi and Roohie Farzaneh and Mohammad Davood Sharifi},
title = {Ketamine in Acute Abdominal Pain in Patients with Lead Poisoning},
journal = {Clinical Medicine Research},
volume = {12},
number = {1},
pages = {9-12},
doi = {10.11648/j.cmr.20231201.12},
url = {https://doi.org/10.11648/j.cmr.20231201.12},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cmr.20231201.12},
abstract = {Introduction: In this study, we investigated the effect of intravenous ketamine administration on the treatment of acute abdominal pain in lead poisoning patients. Methods: In this cross sectional study, we evaluated 20 patients with opium abuse with acute abdominal pain. With cardiac monitoring, 0.25 mg/kg ketamine (maximum dose was considered as 20 milligrams) was administered during 30 to 60 seconds. To control ketamine complications 0.03 mg/kg midazolam (maximum dose was considered as 2 milligrams) was injected slowly during one or two minutes. Patients were observed in the ED for the next 6 hours. Pain score was assessed based on VAS with a serial method, before ketamine administration, every hour for the next two hours and every two hours for four hours. Results: In this study 20 patients were enrolled with mean age of 37.2 ± 4.2 years (range from 30 to 44 yrs.). Repeated measurement test shows significant reduce in pain score after ketamine administration (P=0.001). Five patients report no pain 4 hours after ketamine injection, and 3 of them left the hospital with personal consent. From 17 remaining patients, 13 ones (76.4%) had no pain, and mean VAS score in other 4 patients was 1 or 2. Conclusion: our results show that single dose injectable ketamine is one of the best methods with the least side effects to alleviate acute abdominal pain in patients with drug abuse.},
year = {2023}
}
TY - JOUR T1 - Ketamine in Acute Abdominal Pain in Patients with Lead Poisoning AU - Shaghayegh Rahmani AU - Rana Kolahi Ahari AU - Hamed Shokoohsaremi AU - Roohie Farzaneh AU - Mohammad Davood Sharifi Y1 - 2023/03/28 PY - 2023 N1 - https://doi.org/10.11648/j.cmr.20231201.12 DO - 10.11648/j.cmr.20231201.12 T2 - Clinical Medicine Research JF - Clinical Medicine Research JO - Clinical Medicine Research SP - 9 EP - 12 PB - Science Publishing Group SN - 2326-9057 UR - https://doi.org/10.11648/j.cmr.20231201.12 AB - Introduction: In this study, we investigated the effect of intravenous ketamine administration on the treatment of acute abdominal pain in lead poisoning patients. Methods: In this cross sectional study, we evaluated 20 patients with opium abuse with acute abdominal pain. With cardiac monitoring, 0.25 mg/kg ketamine (maximum dose was considered as 20 milligrams) was administered during 30 to 60 seconds. To control ketamine complications 0.03 mg/kg midazolam (maximum dose was considered as 2 milligrams) was injected slowly during one or two minutes. Patients were observed in the ED for the next 6 hours. Pain score was assessed based on VAS with a serial method, before ketamine administration, every hour for the next two hours and every two hours for four hours. Results: In this study 20 patients were enrolled with mean age of 37.2 ± 4.2 years (range from 30 to 44 yrs.). Repeated measurement test shows significant reduce in pain score after ketamine administration (P=0.001). Five patients report no pain 4 hours after ketamine injection, and 3 of them left the hospital with personal consent. From 17 remaining patients, 13 ones (76.4%) had no pain, and mean VAS score in other 4 patients was 1 or 2. Conclusion: our results show that single dose injectable ketamine is one of the best methods with the least side effects to alleviate acute abdominal pain in patients with drug abuse. VL - 12 IS - 1 ER -